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Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Issued by HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) · via SAM.gov — US federal contract opportunities

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Published
29 Oct 2026
Closes
2 Dec 2026, 20:00 UTC
Reference
ARPA-H-SOL-26-163
Location
United States
Sector
Research, Studies & Evaluation

This notice was amended 2 times

Details changed after publication. Re-check the official notice before bidding.

  • Submission deadline changed from 21 Oct 2026, 19:00 UTC to 2 Dec 2026, 20:00 UTC
    First seen by FreeTender on 29 Oct 2026 — most portals don’t publish when a corrigendum was issued.
  • Submission deadline changed from 18 Oct 2026, 21:00 UTC to 21 Oct 2026, 19:00 UTC
    First seen by FreeTender on 15 Oct 2026 — most portals don’t publish when a corrigendum was issued.

At a glance

HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) in United States has published a tender in research, studies & evaluation: “Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)”. Submissions close on 2 December 2026, 31 days from today. Quote reference ARPA-H-SOL-26-163 in any correspondence with the buyer. FreeTender has recorded 7 notices from this buyer since 2026, 5 of them currently open. There are 76 open research, studies & evaluation notices in United States on FreeTender. Bids are submitted to the buyer through SAM.gov — US federal contract opportunities, not through FreeTender.

Details

HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) is soliciting Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA). Solicitation number ARPA-H-SOL-26-163. Classified under NAICS 541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Product/service code AN13 — BIOMEDICAL (ADVANCED). Responses are due by 02 December 2026 20:00 UTC. Posted on SAM.gov, the US federal contract opportunities system; registration is required to bid.

Amendment 2 (10/29/2026): Numerous changes including, but not limited to,:

• ISO updates in Parts I, II, III and VI; TA1 clarifications; TA2 updates; TA4 updates; Q&A link added • Provides Attachment B1 for TA4 Proposal Requirements and Proposal Volume Templates. • Provides Attachment A2 for TA1 Solution Summary Requirements and Attachment A3 for TA2 Solution Summary Requirements.

Amendment 1 (10/14/2026): Update due dates and/or times of all TAs

SPECTRA will identify and act on autism trajectories, the evolving developmental paths individuals follow across the lifespan from the prenatal period through aging, spanning autism characteristics, co-occurring conditions, and functional outcomes together with the genetic, biological, behavioral, iatrogenic (medical influences), environmental factors and their nonlinear interactions. Rather than examining these factors in isolation, SPECTRA will examine how they combine and interact, including their nonlinear interactions, to produce autism and its co-occurring conditions over time. SPECTRA will also develop technologies that serve two purposes at once: extending reliable assessment beyond the clinic while improving everyday communication, function, and quality of life. The same tools people use to live more fully will also generate the data that drive measurement and personalized care.

Context for bidders

We hold 7 notices from HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H), going back to September 2026 — 5 of them still open. There are 76 open Research, Studies & Evaluation tenders in United States. This one closes in 31 days.

Before you bid on this tender

A quick checklist to help you decide whether to bid and prepare a compliant submission for this research, studies & evaluation opportunity. Always verify the details on the official source.

  • Confirm the exact closing date and time (and time zone) on the official portal — deadlines are strict and can be revised by a corrigendum.
  • Read the full notice and every attached document, including the scope, specifications and any bill of quantities or terms of reference.
  • Check the eligibility criteria — prior similar experience, annual turnover, certifications and registrations — and make sure you qualify before investing effort.
  • Prepare any earnest-money deposit (EMD) or bid security and the required formats early; missing or wrongly-formatted documents are a common cause of rejection.
  • Note how bids must be submitted (online or physical), in what format, and whether a digital signature or portal registration is required.
  • Watch for corrigenda and clarifications right up to the deadline — requirements and dates can change.
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