Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response

HEALTH AND HUMAN SERVICES, DEPARTMENT OF · ADMINISTRATION FOR STRATEGIC PREPAREDNESS AND RESPONSE · BARDA - ASPR / DAAPPO / BARDA DCMA is soliciting Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response. Solicitation number 75A50126R00001_RFP_NPIVS_27. Classified under NAICS 541714 — Research and Development in Biotechnology (except Nanobiotechnology). Product/service code AN12 — R&D- MEDICAL: BIOMEDICAL (APPLIED RESEARCH/EXPLORATORY DEVELOPMENT). Place of performance: DC, USA. Responses are due by 20 November 2026 22:00 UTC. Posted on SAM.gov, the US federal contract opportunities system; registration is required to bid.

BARDA seeks Contractor(s) to support the continuation of the Vaccine Medical Counermeasures (MCM's) for Pandemic Influenza Preparedness and Response Program. Contractors will furnish all the necessary services, qualified personnel, materials, supplies, equipment and facilities (U.S. facilities preferred) not otherwise provided by the USG as needed to provide MCMs, such as vaccines, antigens, and adjuvants, for pandemic preparedness and response or as required in response to a public health emergency; produce antigen and vaccines against influenza virus or other viruses with pandemic potential as required by BARDA; produce antigens, adjuvants, and/or vaccines to support USG efforts to further improve influenza vaccines (for which feasibility data is available); and support rapid regulatory decisions and manufacturing readiness by generating and submitting to FDA all relevant data (e.g., analytical, nonclinical, clinical, and/or chemistry, manufacturing, and controls (CMC)), including data generated during interpandemic periods.

Mandatory Qualification Requirements:

To be eligible for award, the Offeror must produce vaccines against influenza and influenza strains with pandemic potential; must demonstrate a successful experience in the manufacturing of influenza vaccine by:

1. Holding a U.S. influenza vaccine license; or

2. Have developed an influenza vaccine as evidenced by

a. Submission of a Biologics License Application (BLA) for seasonal or pandemic influenza vaccine Please see full solicitation details and proposal submission instructions detailed in attachments 01-19 of this notice.