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ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Issued by HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) · via SAM.gov — US federal contract opportunities

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Published
16 Sept 2026
Closes
7 Oct 2026, 18:00 UTC
Reference
ARPA-H-SOL-26-165
Location
United States
Sector
Research, Studies & Evaluation

Details

HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) is soliciting ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening. Solicitation number ARPA-H-SOL-26-165. Classified under NAICS 541714 — Research and Development in Biotechnology (except Nanobiotechnology). Product/service code AN13 — BIOMEDICAL (ADVANCED). Responses are due by 07 October 2026 18:00 UTC. Posted on SAM.gov, the US federal contract opportunities system; registration is required to bid.

The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth. ARPA-H anticipates multiple Other Transaction awards resulting from this announcement. Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165

Context for bidders

We hold 4 notices from HEALTH AND HUMAN SERVICES, DEPARTMENT OF · NATIONAL INSTITUTES OF HEALTH · NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H), going back to September 2026 — 4 of them still open. There are 57 open Research, Studies & Evaluation tenders in United States. This one closes in 21 days.

Before you bid on this tender

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