Innovative advanced
Issued by European Commission · via EU Funding & Tenders Portal
- Published
- 4 Oct 2026
- Closes
- 2 Feb 2027
- Reference
- HORIZON-CL4-2027-01-MAT-PROD-22
- Location
- European Union
- Sector
- Healthcare & Pharma
At a glance
European Commission in European Union has published a funding call in healthcare & pharma: “Innovative advanced”. Submissions close on 2 February 2027, 121 days from today. Quote reference HORIZON-CL4-2027-01-MAT-PROD-22 in any correspondence with the buyer. FreeTender has recorded 353 notices from this buyer since 2026, 350 of them currently open. There are 32 open healthcare & pharma notices in European Union on FreeTender. Bids are submitted to the buyer through EU Funding & Tenders Portal, not through FreeTender.
Details
Expected Outcome:
- Reducing dependencies of critical and strategic raw materials through partial or total substitution by safe and sustainable innovative advanced materials and/or via more efficient use of critical and strategic raw materials in production processes;
- Speeding up the innovation cycle within value chain(s) important for European industry;
- Enhancing competitiveness of the industries and operational costs, while making supply chains more secure;
- New or improved production processes, innovative advanced materials and products that are safer and more sustainable, supporting a clean and autonomous economy; and
- Demonstrating how the safe and sustainable by design (SSbD) chemicals and materials framework can guide innovation.
Scope:
The focus of this topic is on alternatives for the substitution or more efficient use of critical and strategic raw materials [1] . The design and development of innovative advanced materials (IAMs) and processes should lead to an innovation cycle covering the (re)design of materials and production processes, and the integration of IAMs into products. Proposals should develop IAMs or process technologies to replace or reduce the use of critical and strategic raw materials in strategic areas and sectors such as energy, mobility, construction, electronics, medical devices or chemical industries. Proposals should address one or several of the following approaches:
- Design, development and production with targets on performance, safety and sustainability of IAMs substituting or making a more efficient use of critical and strategic raw materials.
- Innovative industrial processes for the reduction of the use of critical and strategic raw materials focussed on optimizing process safety, sustainability, flexibility, scalability, cost-efficiency.
- Co-development strategies for IAMs and industrial processes. These strategies should demonstrate the value of co-development through specific use cases while maintaining broad relevance across various materials and process types.
Proposals should demonstrate clear use case(s), market and potential to grow. The substitution barriers for the selected applications should be identified and a driving mechanism for a maximal substitution in the targeted value chains proposed. The scope includes necessary adaptations of related processes and technologies to ensure alignment with and integration in industrial manufacturing in order to facilitate the uptake of the developed solutions. If relevant, challenges for the adaption of existing production lines should be identified and solutions proposed. Proposals should demonstrate that SSbD framework [2] will be applied throughout the innovation process, showing that safety and sustainability principles are actively integrated and influence decision-making in a transparent and traceable way, and ensure that the data generated within the proposal may be shared with the Common Data Platform for Chemicals. The new alternatives to be developed should meet the technical functions required in the specific applications while aligning their innovation process decision making with such framework. Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination. Proposals are encouraged to cooperate with relevant projects. Where relevant, proposals should actively contribute to and cooperate with the EU Innovation and Substitution Hub(s) [3] . Proposals should allocate the necessary resources to the proposed activities This topic implements the co-programmed European partnerships Innovative Advanced Materials for the EU (IAM4EU) and Processes4Planet. Technology Readiness Level - Technology readiness level expected from completed projects Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.
[1] https: //rmis.jrc.ec.europa.eu/eu-critical-raw-materials ; as well as Annex I and II of the
[2] See documents defining the SSbD framework on: https://ec.europa.eu/info/research-and-innovation/research-area/industrial-research-and-innovation/key-enabling-technologies/advanced-materials-and-chemicals_en [3] European Chemicals Industry Action Plan - European Commission
Submissions open on 13 October 2026.
Part of call HORIZON-CL4-2027-01
Type of action: HORIZON Innovation Actions
Programme period: 2021 - 2027
Priorities: DigitalAgenda, PART-COPROGR, AI, PART-COPROGR
"> General conditions
1. Admissibility Conditions: Proposal page limit and layout
In order to include a business case and exploitation strategy, as outlined in the introduction to this Destination, the page limit is exceptionally extended by 3 pages.
Admissibility conditions are described in Annex A and Annex E of the Horizon Europe Work Programme General Annexes.
Proposal page limits and layout: described in Part B of the Application Form available in the Submission System.
2. Eligible Countries
described in Annex B of the Work Programme General Annexes. A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon Europe projects. See the information in the Horizon Europe Programme Guide .
3. Other Eligible Conditions
To increase EU resilience in raw materials supply chains and thus reduce the serious risk to the Union's strategic assets, economic and societal interests, autonomy and security associated with the current EU reliance on a few third countries for critical raw materials, by increasing sustainable and responsible sourcing of primary and secondary raw materials necessary to enable the green and digital transition and in alignment with the objectives of the Critical Raw Materials Act[[Regulation (EU) 2024/1252 of the European Parliament and of the Council of 11 April 2024 establishing a framework for ensuring a secure and sustainab
Context for bidders
We hold 353 notices from European Commission, going back to August 2026 — 350 of them still open. They buy mostly in Water & Environment, Forestry & Wildlife and IT & Telecom. There are 32 open Healthcare & Pharma tenders in European Union. This one closes in 121 days.
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- Improving socio-economic outcomes for persons with dementia and informal caregivers· closes 4 May
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Before you bid on this tender
A quick checklist to help you decide whether to bid and prepare a compliant submission for this healthcare & pharma opportunity. Always verify the details on the official source.
- Confirm the exact closing date and time (and time zone) on the official portal — deadlines are strict and can be revised by a corrigendum.
- Read the full notice and every attached document, including the scope, specifications and any bill of quantities or terms of reference.
- Check the eligibility criteria — prior similar experience, annual turnover, certifications and registrations — and make sure you qualify before investing effort.
- Prepare any earnest-money deposit (EMD) or bid security and the required formats early; missing or wrongly-formatted documents are a common cause of rejection.
- Note how bids must be submitted (online or physical), in what format, and whether a digital signature or portal registration is required.
- Watch for corrigenda and clarifications right up to the deadline — requirements and dates can change.
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