Funding Opportunity for Infectious Disease Research Using Human Tissue Models (US)

The National Institutes of Health (NIH) is inviting applications for the establishment of Translational Centers using Microphysiological Systems for Infectious Diseases (TCMID). This discretionary funding opportunity aims to develop advanced in vitro models for infectious diseases to enhance research and regulatory processes. Applications must be submitted by 29 January 2027. This grant supports the creation of a consortium of Translational Centers using Microphysiological Systems (MPS) specifically for infectious diseases research. The initiative aims to refine human tissue models that emulate infectious diseases, aligning them with regulatory standards to facilitate their adoption in product development and regulatory processes. This approach is part of a broader effort to implement New Approach Methodologies (NAMs) in research, which includes reducing the reliance on animal testing.

Eligible applicants include:

The primary focus is on developing and refining human tissue models for studying infectious diseases. These models should be validated to meet regulatory standards and aim to enhance the development of safer medical interventions. This funding opportunity is crucial for advancing research methodologies that reduce the dependency on animal models while improving the accuracy and efficiency of infectious disease research. By supporting innovative MPS approaches, this initiative seeks to accelerate the development of effective and safer treatments, ultimately benefiting public health and reducing costs. What types of organizations are eligible to apply? State governments, higher education institutions, certain nonprofits, small businesses, tribal organizations, and several others, including foreign entities, can apply. What is the total funding available for this opportunity? The estimated total program funding is $7,000,000. Is there a cost-sharing requirement? No, cost-sharing is not required for this opportunity. What is the application deadline? Applications must be submitted by 29 January 2027. How do I submit my application? Applications should be submitted electronically through Grants.gov by the deadline. Interested applicants should thoroughly review the official announcement and application instructions on Grants.gov to ensure compliance with all requirements. Engage with relevant stakeholders within your organization to prepare a competitive proposal well before the submission deadline.